Teratogenic effect of hydrosalpinx fluid in humans?

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چکیده

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Teratogenic effect of hydrosalpinx fluid in humans?

We read with great interest the manuscript by Chan et al. (2003) examining the teratogenicity of hydrosalpinx ¯uid (HF) using a whole rate embryo culture model. Mechanisms of HF formation and its effects on IVF and embryo transfer outcome have been recently reviewed (Ajonuma et al., 2002). Previous studies were conducted during early embryo development when HF that re¯uxed into the uterine cavi...

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Is hydrosalpinx fluid cytotoxic?

Accumulation of oviductal fluid in the ampullar lumen as a result of occlusion of the infundibulum is referred to as hydrosalpinx. A low pregnancy rate (10%) after in-vitro fertilization (IVF) in hydrosalpinx patients and a relatively high incidence (50%) of abortions during the first trimester suggested that leakage of this fluid into the uterine cavity may exert a cytotoxic effect on the deve...

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Adverse effects of hydrosalpinx fluid on sperm motility and survival.

The negative impact of hydrosalpinx on IVF outcome is well recognized but some reports indicate that tubal infertility with hydrosalpinx is a heterogeneous entity and may have different effects on the outcome. The embryotoxic effects of hydrosalpinx fluid (HF) have been documented in mouse but not human embryos. This study examined the effects of HF on sperm motility and survival after various ...

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ژورنال

عنوان ژورنال: Human Reproduction

سال: 2003

ISSN: 1460-2350

DOI: 10.1093/humrep/deg417